REYATAZ

Indication: REYATAZ (atazanavir sulfate) is a prescription medicine used in combination with other medicines to treat people 6 years of age and older who are infected with the human immunodeficiency virus (HIV). REYATAZ has been studied in a 48-week trial in patients who have taken anti-HIV medicines and a 96-week trial in patients who have never taken anti-HIV medicines. REYATAZ does not cure HIV or AIDS and you may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections.

 
 
REYATAZ can help lower your viral load to undetectable. Individual results may vary. REYATAZ can help lower your viral load to undetectable. Individual results may vary. Click here REYATAZ studies have included women and men.
 

Getting Help Paying for REYATAZ

If your doctor has prescribed REYATAZ® (atazanavir sulfate) as part of HIV combination therapy and you have concerns about paying for your prescription, read about the programs below to find out if you may be eligible to get help paying for REYATAZ. Restrictions apply.

BMS Co-Pay Assist Program

Sponsored by Bristol-Myers Squibb (BMS), the Co-Pay Assist Program offers eligible participants help covering up to the first $400 per monthly co-pay (for up to a year).

Find out if you can save on REYATAZ. Call 1-888-281-8981 or visit www.bms3assist.com/copay for details.

†Subject to terms and conditions. Restrictions apply.

BMS Patient Assistance Programs

Patients who need help paying for their Bristol-Myers Squibb medicines, including REYATAZ® (atazanavir sulfate), may be eligible to get assistance through a number of BMS patient assistance programs.

Get program details, review eligibility requirements, and learn how to apply at the
BMS3assist site.

Visit www.bms3assist.com or call 1-888-281-8981 to learn about available assistance programs.

Important Safety Information

About REYATAZ

Do not take REYATAZ if you are allergic to REYATAZ or to any of its ingredients.

Do not take REYATAZ® (atazanavir sulfate) if you are taking the following medicines due to potential for serious, life-threatening side effects or death:
Versed® (midazolam) when taken by mouth, Halcion® (triazolam), ergot medicines (dihydroergotamine, ergonovine, ergotamine, and methylergonovine such as Cafergot®, Migranal®, D.H.E. 45®, ergotrate maleate, Methergine®, and others),
Propulsid® (cisapride), or Orap® (pimozide).

Do not take REYATAZ with the following medicines due to potential for serious side effects:
Camptosar® (irinotecan), Crixivan® (indinavir), Mevacor® (lovastatin),
Zocor® (simvastatin), Uroxatral® (alfuzosin), or Revatio® (sildenafil).

Do not take REYATAZ (atazanavir sulfate) with the following medicines as they may lower the amount of REYATAZ in your blood, which may lead to increased HIV viral load and resistance to REYATAZ or other anti-HIV medicines:
rifampin (also known as Rimactane®, Rifadin®, Rifater®, or Rifamate®),
St. John's wort (Hypericum perforatum)-containing products, or Viramune® (nevirapine).

Serevent Diskus® (salmeterol), Advair® (salmeterol with fluticasone),
Victrelis® (boceprevir), and Vfend® (voriconazole) are not recommended with REYATAZ.

The above lists of medicines are not complete. Taking REYATAZ® (atazanavir sulfate) with some other medicines may require your therapy to be monitored more closely or may require a change in dose or dose schedule of REYATAZ or the other medicine. Discuss with your healthcare provider all prescription and non-prescription medicines, vitamin and herbal supplements, or other health preparations you are taking or plan to take.

Tell your healthcare provider if you are pregnant or plan to become pregnant. REYATAZ (atavanazir sulfate) use during pregnancy has not been associated with an increase in birth defects. Pregnant women have experienced serious side effects when taking REYATAZ with other HIV medicines called nucleoside analogues. After your baby is born, tell your healthcare provider if your baby's skin or the white part of his/her eyes turns yellow. Do not breastfeed if you are HIV-positive.

Also tell your healthcare provider if you have end-stage kidney disease managed with hemodialysis or severe liver dysfunction.

Tell your healthcare provider right away if you have any side effects, symptoms, or conditions, including the following:

  • Mild rash (redness and itching) without other symptoms sometimes occurs in patients taking REYATAZ, most often in the first few weeks after the medicine is started, and usually goes away within 2 weeks with no change in treatment.
  • Severe rash may develop with other symptoms that could be serious and potentially cause death. If you develop a rash with any of the following symptoms, stop using REYATAZ® (atazanavir sulfate) and call your healthcare provider right away:
    • - Shortness of breath
    • - General ill-feeling or "flu-like" symptoms
    • - Fever
    • - Muscle or joint aches
    • - Conjunctivitis (red or inflamed eyes, like "pink-eye")
    • - Blisters
    • - Mouth sores
    • - Swelling of your face
  • Yellowing of the skin and/or eyes may occur due to increases in bilirubin levels in the blood (bilirubin is made by the liver).
  • A change in the way your heart beats may occur. You may feel dizzy or lightheaded. These could be symptoms of a heart problem.
  • Diabetes and high blood sugar may occur in patients taking protease inhibitor medicines like REYATAZ® (atazanavir sulfate). Some patients may need changes in their diabetes medicine.
  • If you have liver disease, including hepatitis B or C, it may get worse when you take anti-HIV medicines like REYATAZ.
  • Kidney stones have been reported in patients taking REYATAZ. Signs or symptoms of kidney stones include pain in your side, blood in your urine, and pain when you urinate.
  • Gallbladder disorders (including gallstones and gallbladder inflammation) have been reported in patients taking REYATAZ. Signs or symptoms of gallstones include pain in the right or middle upper stomach, fever, nausea and vomiting, or yellowing of skin and whites of the eyes.
  • Some patients with hemophilia have increased bleeding problems with protease inhibitor medicines like REYATAZ.
  • Changes in body fat have been seen in some patients taking anti-HIV medicines. The cause and long-term effects are not known at this time.
  • Immune reconstitution syndrome has been seen in some patients with advanced HIV infection (AIDS) and a history of opportunistic infection. Signs and symptoms of inflammation from previous infections may occur soon after starting anti-HIV treatment, including REYATAZ.

Other common side effects of REYATAZ taken with other anti-HIV medicines include: nausea; headache; stomach pain; vomiting; diarrhea; depression; fever; dizziness;
trouble sleeping; numbness, tingling, or burning of hands or feet; and muscle pain.

You should take REYATAZ® (atazanavir sulfate) once daily with food (a meal or snack). Swallow the capsules whole; do not open the capsules. You should take REYATAZ and your other anti-HIV medicines exactly as instructed by your healthcare provider.

Click here for U.S. Full Prescribing Information, including Patient Information.

*Undetectable was defined as a viral load of less than 400 copies/mL.

Talk to your doctor

Ask your doctor about treatment that is right for you.

 

Learn how REYATAZ can help

Once-daily REYATAZ in combination therapy has been shown to be effective in treating HIV. It can help raise your CD4+ cell count and lower your viral load to undetectable.* REYATAZ does not cure HIV or AIDS and you may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections.